The position paper published in November 2022 reflects the key elements that Eurogroup for Animals would like to see included in a European-wide strategy for the transition to non-animal science. These include a clear statement that transitioning to non-animal science is a desirable and achievable goal, along with a strong commitment to work to get there; clear milestones; identification and prioritisation of key reserach areas where resources and efforts need to be targeted; an appropriate level of funding to support the development and uptake of new, advanced non-animal technologies; large scale support for building key infrastructure that would allow fuller exploitation of existing and new alternative methods; education and training in non-animal technologies; and more robust project evaluation and authorisation processess, and peer review and publication policies from scientific journals.