NIH funding for NAM development announced

The National Institutes of Health (NIH) Common Fund has announced a Notice of Intent to Publish a Funding Opportunity for the Complement Animal Research in Experimentation (Complement-ARIE) program. Complement-ARIE will accelerate the development, standardization, validation, and use of human-based new approach methodologies (NAMs) that more accurately model human biology, and complement, or in some cases, replace traditional research models.

Complement-ARIE program goals include:

• To better model and understand human health and disease outcomes across diverse populations.
• To develop NAMs that provide insight into specific biological processes or disease states.
• To validate mature NAMs to support regulatory use and standardization.
• To complement traditional models and make biomedical research more efficient and effective.

The Complement-ARIE program plans to issue a Notice of Funding Opportunity to support the Complement-ARIE Comprehensive NAMs Technology Development Centers. The goal/intent of these Centers is to stimulate the development of combinatorial NAMs in the areas of greatest need.

Publication of the funding opportunity is anticipated on October 18. The Notice of Intent to Publish a Funding Opportunity is available at https://go.nih.gov/iiuNC9v. More information about the Complement-ARIE Program is available at https://commonfund.nih.gov/complementarie/faqs. Interested persons can keep up to date with future announcements by signing up for the Complement-ARIE listserv at https://list.nih.gov/cgi-bin/wa.exe?SUBED1=COMPLEMENT-ARIE&A=1?