[Investigations of the endotoxin content of veterinary vaccines] [Article in German]

Klaus Cussler; Hannelore Godau; Heike Gyra

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Published: Jan 1, 1994

Klaus Cussler, Hannelore Godau, Heike Gyra
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Abstract

Vaccines composed of gram negative bacteria contain endotoxin in considerable amounts. This may result in adverse effects after vaccination of sensitive animals. For reasons of safety and animal welfare the endotoxin level of veterinary vaccines should be limited. The limulus amebocyte lysate test is suitable to check the endotoxin content in most vaccines. Safety tests in animals should only be performed if the results of the limulus test are satisfactory.

How to Cite

Cussler, K., Godau, H. and Gyra, H. (1994) “[Investigations of the endotoxin content of veterinary vaccines] [Article in German]”, ALTEX - Alternatives to animal experimentation, 11(Supp. 1), pp. 24–29. Available at: https://altex.org/index.php/altex/article/view/2037 (Accessed: 17 May 2025).

Issue

Vol. 11 No. Supp. 1 (1994): Paul-Ehrlich-Seminar über Tierschutzaspekte bei der Zulassung und Prüfung von immunologischen Arzneimitteln

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Articles are distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is appropriately cited (CC-BY). Copyright on any article in ALTEX is retained by the author(s).

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