Non-animal models: Complexity for interactions…Connecting science

Francesca Caloni; Alessandra Cazzaniga; Arno C. Gutleb; Thomas Hartung; Helena Kandarova; Giulia Ranaldi; Hassan Rashidi; Doris Wilflingseder; Saliha Moutaharrik

doi:10.14573/altex.2407181

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Published: Oct 22, 2024

DOI: https://doi.org/10.14573/altex.2407181

Francesca Caloni , Alessandra Cazzaniga, Arno C. Gutleb, Thomas Hartung, Helena Kandarova, Giulia Ranaldi, Hassan Rashidi, Doris Wilflingseder, Saliha Moutaharrik
[show affiliations]

Francesca Caloni

Università degli Studi di Milano, Department of Environmental Science and Policy (ESP), Milan Italy

Alessandra Cazzaniga

Fondazione Alessandro Volta, Italy

Arno C. Gutleb

Luxembourg Institute of Science and Technology, Environmental Sustainability Assessment and Circularity (SUSTAIN) Unit, Luxembourg

Thomas Hartung

Center for Alternatives to Animal Testing, Bloomberg School of Public Health and Whiting School of Engineering, Doerenkamp-Zbinden-Chair for Evidence-based Toxicology, Johns Hopkins University, Baltimore, MD, USA; University of Konstanz, CAAT-Europe, Konstanz, Germany

Helena Kandarova

Centre of Experimental Medicine (CEM), Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, Slovakia; Faculty of Chemical and Food Technology (FChFT), Institute of Biochemistry and Microbiology, Slovak University of Technology (STU), Bratislava, Slovakia

Giulia Ranaldi

Food and Nutrition Research Centre, Council for Agricultural Research and Economics, CREA-AN, Rome, Italy

Hassan Rashidi

NIHR Great Ormond Street Hospital Biomedical Research Centre, UCL Great Ormond Street Institute of Child Health, University College London, London, UK

Doris Wilflingseder

Institute of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria; University of Veterinary Medicine, Department of Pathophysiology, Infectiology Unit, Vienna, Austria

Saliha Moutaharrik

Università degli Studi di Milano, Department of Pharmaceutical Sciences (DISFARM), Section of Pharmaceutical Technology and Legislation “M.E. Sangalli”, Milan, Italy

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How to Cite

Caloni, F. (2024) “Non-animal models: Complexity for interactions…Connecting science”, ALTEX - Alternatives to animal experimentation, 41(4), pp. 666–668. doi: 10.14573/altex.2407181.

Issue

Vol. 41 No. 4 (2024)

Section

Meeting Reports

This work is licensed under a Creative Commons Attribution 4.0 International License.

Articles are distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is appropriately cited (CC-BY). Copyright on any article in ALTEX is retained by the author(s).

References

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Hartung, T. (2023b). ToxAIcology – The evolving role of artificial intelligence in advancing toxicology and modernizing regulatory science. ALTEX 40, 559-570. doi:10.14573/altex.2309191

Kandarova, H. and Pôbiš, P. (2024). The “Big Three” in biocompatibility testing of medical devices: Implementation of alternatives to animal experimentation-are we there yet? Front Toxicol 5, 1337468. doi:10.3389/ftox.2023.1337468

Kleinstreuer, N. and Hartung, T. (2024). Artificial intelligence (AI) – It’s the end of the tox as we know it (and I feel fine). Arch Toxicol 98, 735-754. doi:10.1007/s00204-023-03666-2

Luvanda, M. K., Posch, W., Noureen, A. et al. (2021). Dexamethasone creates a suppressive microenvironment and promotes Aspergillus fumigatus invasion in a human 3D epithelial/immune respiratory model. J Fungi 7, 221. doi:10.3390/jof7030221

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Posch, W., Vosper, J., Noureen, A. et al. (2021). C5aR inhibition of nonimmune cells suppresses inflammation and maintains epithelial integrity in SARS-CoV-2-infected primary human airway epithelia. J Allergy Clin Immunol 147, 2083-2097.e6. doi:10.1016/j.jaci.2021.03.038

Sewell, F., Alexander-White, C., Brescia, S. et al. (2024). New approach methodologies (NAMs): Identifying and overcoming hurdles to accelerated adoption. Toxicol Res 13, tfae044. doi:10.1093/toxres/tfae044

Smirnova, L., Morales Pantoja, I. E. and Hartung, T. (2023). Organoid intelligence (OI) – The ultimate functionality of a brain microphysiological system. ALTEX 40, 191-203. doi:10.14573/altex.2303261

Zaderer, V., Dichtl, S., Posch, W. et al. (2023). GlyPerA™ effectively shields airway epithelia from SARS-CoV-2 infection and inflammatory events. Respir Res 24, 88. doi:10.1186/s12931-023-02397-3

Zaderer, V., Diem, G., Posch, W. et al. (2024). P80 natural essence spray and lozenges provide respiratory protection against Influenza A, B, and SARS-CoV-2. Respir Res 25, 102. doi:10.1186/s12931-024-02718-0

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