Metze, Konradin, Fernanda Aparecida Borges da Silva, and Irene Lorand-Metze. 2018. “Lowering the P-Value from 0.05 to 0.005 Conflicts With the 3R Rules – an Advocacy for Alternatives to Hypothesis Testing With the P-Value Approach”. ALTEX - Alternatives to Animal Experimentation 35 (4):516-17. https://doi.org/10.14573/altex.1807091.