The European Food Safety Agency (EFSA) is developing TKPlate, an online platform that offers a space and a suite of tools for scientists and regulators to model and predict toxicokinetic and toxicodynamic properties of chemicals found in food and feed. TKPlate will support modeling and predicting the toxicity of chemicals and what happens to them inside humans and animals, enabling reduction of animal use for this purpose. An overview of TKPlate is available at A detailed description of the platform is published in an article (Dorne et al.) in the EFSA Journal, available at