Latest Articles

Latest Articles

Latest Articles are manuscripts that have recently been accepted for publication in ALTEX but have not yet undergone editing, layout, and proofreading. They are replaced by a final version with the same doi upon print publication in an issue of ALTEX.

Software tools for systematic review literature screening and data extraction: Qualitative user experiences from succinct formal tests

Cathalijn H. C. Leenaars, Frans Stafleu, André Bleich
Published: Oct 10, 2024
accepted manuscript

The Virtual Human Platform for Safety Assessment (VHP4Safety) project: Next generation chemical safety assessment based on human data

Anne Kienhuis, Cyrille Krul, Jacqueline van Engelen, Chris T. Evelo, Ellen Hessel, Jarno Hoekman, Nynke Kramer, Esmeralda Krop, Rosalinde Masereeuw, Ellen Moors, Simona O. Negro, Albert Piersma, Raymond Pieters, Marc Teunis, Egon Willighagen, Juliette Legler
Published: Oct 9, 2024
accepted manuscript

Characterization of the C17.2 cell line as testing system for endocrine disruption-induced developmental neurotoxicity

Andrea Cediel-Ulloa, Roseline Awoga, Arif Dönmez, Ximiao Yu, Anda Gliga, Kristina Attoff, Anna Forsby, Joëlle Rüegg
Published: Sep 6, 2024
accepted manuscript sup

Performance of the DASF compared to other combinations of OECD NAMs for eye hazard identification of surfactants

Nathalie Alépée, Karsten R. Mewes, Takayuki Abo, Alessandra Cavarzan, Chelsea Odriscoll, Els Adriaens
Published: Aug 28, 2024
accepted manuscript sup

Development of a monoclonal antibody sandwich ELISA for the quality control of human and animal tetanus vaccines

Laura Hassall, Daniel Alejandro Yara, Rebecca Riches-Duit, Peter Rigsby, Alexandre Dobly, Maxime Vermeulen, Antoine Francotte, Bart Faber, Paul Stickings
Published: Aug 23, 2024
accepted manuscript

Predicting acute oral toxicity using AcutoX: An animal product-free and metabolically relevant human cell-based test

Thomas Ward, Hannah Goldsby, Michael Connolly, Clive Roper, Carol Treasure
Published: Aug 19, 2024
accepted manuscript

Sensitivity analysis and quality indicators for an in vitro oral irritation assay

Robert Gutierrez, Blaza Toman, Yong Ma, John T. Elliott, Elijah J. Petersen
Published: Aug 7, 2024
accepted manuscript sup

Potential value of animal microphysiological systems

Paul C. Brown, Barry H. Hooberman, Brianna L. Skinner, Claudia Wrzesinski, Dayton M. Petibone, Kevin A. Ford, Kristi Muldoon-Jacobs, Kyung E. Sung, Luis G. Jr. Valerio, Nakissa N. Sadrieh, Paul C. Howard, Peter L. Goering, Shelby A. Skoog, Suzanne C. Fitzpatrick, Tracy Chen, Tracy C. MacGill, Donna L. Mendrick
Published: Aug 7, 2024
accepted manuscript

A proof-of-concept rat toxicity study highlights the potential utility and challenges of virtual control groups

Roxanne Andaya, Ruth Sullivan, Tony Pourmohamad, Matt Hayes, Pierre Maliver, Steven Laing, Catrin Hasselgren, Noel Dybdal, Adeyemi O. Adedeji, Lennart T. Anger
Published: Aug 7, 2024
accepted manuscript sup

A sensitive cell-based assay for testing potency of Botulinum neurotoxin type A

Ceyda Caliskan, Deniz Simsek, Charlotte Leese, Ciara Doran, Elizabeth Seward, Andrew A. Peden, Bazbek Davletov
Published: Jul 22, 2024
accepted manuscript sup

Data-driven derivation of an adverse outcome pathway linking vascular endothelial growth factor receptor (VEGFR), endocrine disruption, and atherosclerosis

Daniel Ehrlich, Shagun Krishna, Nicole Kleinstreuer
Published: Jul 8, 2024
accepted manuscript sup1 sup2

The road to virtual control groups and the importance of proper body-weight selection

Alexander Gurjanov, Lea A. I. Vaas, Thomas Steger-Hartmann
Published: May 22, 2024
accepted manuscript sup