NICEATM has released Version 4.0.2 of the Integrated Chemical Environment (ICE). ICE provides chemical safety data and property predictions as well as tools to help query, review, and contextualize these data. ICE is available at

Key features implemented in ICE 4.0.2 are: 

  • New data visualizations for Search tool query summary results.
  • Updated filter chain options in Search.
  • New overlays for data comparisons in the In Vitro to In Vivo Extrapolation (IVIVE) tool.
  • Curve Surfer tool optimization.
  • Updated cHTS data from the Invitrodb v3.5 release.
  • Improved support for chemical name searching in the ICE REST API.

Demonstrations of ICE and other NICEATM computational tools will be given Monday, March 11 through Wednesday, March 13 at the Society of Toxicology (SOT) 2024 annual meeting in Salt Lake City, UT. Visit to view the demonstration schedule.