[Computer-aided drug design - an alternative to animal testing in the pharmacological screening] [Article in German]

Angelo Vedani

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Published: Apr 1, 1991

Angelo Vedani
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Abstract

By means of graphical and numerical simulation of the binding of a biological key molecule to a receptor, Computer-Aided Drug Design (CADD) allows the semi-quantitative prediction of the activity of potential drug molecules. New drugs can be tailor-made for a specific receptor without animal testing; substances with little or no pharmacological activity are unambiguously identified and removed from the evaluation process before preclinical "in vivo" tests become necessary. Two methods, direct CADD and Receptor Mapping are presented.

How to Cite

Vedani, A. (1991) “[Computer-aided drug design - an alternative to animal testing in the pharmacological screening] [Article in German]”, ALTEX - Alternatives to animal experimentation, 8(1), pp. 39–60. Available at: https://altex.org/index.php/altex/article/view/1850 (Accessed: 4 October 2024).

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Vol. 8 No. 1 (1991)

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Articles

Articles are distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is appropriately cited (CC-BY). Copyright on any article in ALTEX is retained by the author(s).

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