[Possibilities of cell culture methods and alternatives to animal tests in toxicology] [Article in German]
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Abstract
A current basic shift in the ethical, scientific and commercial engagement for alternatives to animal experimentation is described which is a prerequisite for their stronger use in practice. A review on the various alternatives is given with emphasis on cell culture methods and toxicology. The most promising alternatives are prospectively summarized and some known limits of in vitro systems are discussed in comparison with the value of results from animal experimentation and in the context of safety evaluations in toxicology.
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