20 Years 3R Research Foundation Switzerland

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Franz P. Gruber
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Peter Maier and Hugo Wick



Pierre Aeby, François Python and Carsten Goebel
Skin sensitisation: Understanding the in vivo situation for the development of reliable in vitro test approaches

Margarete Arras
Improvement of pain therapy in laboratory mice

Yara Banz and Robert Rieben
Exploring natural anticoagulation by endothelial cells: A novel in vitro model

Nicolau Beckmann
Non-invasive methods: Investigation of airways diseases by MRI in rats

Gerd Bicker, Andrea Gierse, Saime Tan and François Paquet-Durand
Simulation of stroke-related damage in cultured human nerve cells

Frank O. Bootz and Felix R. Wolf
Animal-free screening of biological materials for contamination by rodent viruses

Arie Bruinink and Peter Maier
Identification of neurotoxic chemicals in cell cultures

Karl Fent
Permanent fish cell cultures as important tools in ecotoxicology

Andrew Hemphill
Generation of parasite cysts in cultured cells instead of living animals

Paul Honegger and Beatriz Pardo
Aggregating brain cell cultures: Investigation of stroke related brain damage

Rok Humar, Lourdes Sanchez de Miguel, Fabrice N. Kiefer, Edouard J. Battegay: Formation of new blood vessels in the heart can be studied in cell cultures

Thomas Kröber and Patrick Guerin
The tick blood meal: From a living animal or from a silicone membrane?

Regine Landmann-Suter
Generation and use of a mouse Kupffer cell line

Claudia Mertens and Thomas Rülicke
Welfare assessment and phenotype characterisation of transgenic mice

Werner J. Pichler
Predicting drug hypersensitivity by in vitro tests

Valeska Reichel, Carsten Baehr and Gert Fricker
From blood to brain and vice versa: Transport processes in choroid plexus can be studied in vitro

Geoff Richards, Martin J. Stoddart, Angharad E. Simpson and Pamela I. Furlong Establishing a 3D ex vivo culture system for investigations of bone metabolism and biomaterial interactions

Stefanie Schindler, Stefan Fennrich, Reto Crameri, Thomas W. Jungi, Thomas Montag, Thomas Hartung
Fever in the test tube – towards a human(e) pyrogen test

Angelo Vedani, Markus A. Lill and Max Dobler
Predicting the toxic potential of drugs and chemicals in silico

Eva Waiblinger and Barbara König
Housing and husbandry conditions affect stereotypic behaviour in laboratory gerbils 67

Hanno Würbel
Environmental enrichment does not disrupt standardization of animal experiments



Anna Bogdanova and Johannes Vogel
Isolated, autologous blood-perfused heart: Replacement of heterotopic heart transplantation

Paolo Cinelli
Assessment of pain and stress in mice by monitoring gene expression changes

Pierre Cosson
A non-mammalian system to study bacterial infections

Beate Escher
Development of QSAR-models for classification and prediction of baseline toxicity and of uncoupling of energy transduction

Beate Escher and Jung-Hwan Kwon
Development of an in vitro system for modeling bioaccumulation of neutral, ionizable, and metabolically active organic pollutants in fish system

Paul Flecknell, Jon Gledhill and Claire Richardson
Assessing animal health and welfare and recognising pain and distress

Marianne Geiser and Doris Lang
In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction

Norbert Goebels
Organotypic CNS slice cultures as an in vitro model for immune mediated tissue damage and repair in multiple sclerosis

Regina Hofmann-Lehmann and Ludwig Hoelzle
Development of in vitro strategies to propagate and characterize hemotrophic mycoplasmas

Cynthia Lee and Mauro Alini
The development of an in vitro intervertebral disc organ culture

Stephen L. Leib
An in vitro model of central nervous system infection and regeneration: Neuronal stem cells as targets of brain damage and regenerative therapies in bacterial meningitis

Alexander Mathis
Development of a three-dimensional enteric cell culture model for In vitro studies of the intestinal eukaryotic parasites Cryptosporidium spp.

Christoph Mueller
Establishment of a murine syngeneic co-culture system of intestinal epithelial cells with intraepithelial T lymphocyte subsets

Omolara Ogunshola
Development of a novel multicellular 3-dimensional blood brain barrier in vitro model

Elisabetta Padovan
Adjuvanticity of microbial-derived particles and synthetic analogs in vitro

Nicolas Ruggli and Artur Summerfield
Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates

Claudio Strebel
Information on serum free cell lines, an interactive database


Article Details

How to Cite
Gruber, F. P. (2007) “20 Years 3R Research Foundation Switzerland”, ALTEX - Alternatives to animal experimentation, 24(Spec. Issue), pp. 1–104. Available at: https://altex.org/index.php/altex/article/view/2210 (Accessed: 14 July 2024).